Interacting Slow and Fast Dynamics in Precise Spiking-Bursting Neurons

نویسندگان

  • Fabiano Baroni
  • Joaquín J. Torres
  • Pablo Varona
چکیده

We have explored the role of the interaction of slow and fast intracellular dynamics in generating precise spiking-bursting activity in a model of the heartbeat central pattern generator of the leech. In particular we study the effect of calcium-dependent currents on the neural signatures generated in the circuit. These neural signatures are cell-specific interspike intervals in the spiking-bursting activity of each neuron. Our results show that the slow dynamics of intracelullar calcium concentration can regulate the precision and shape of the neural signatures.

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تاریخ انتشار 2005